Dr. George is an Assistant Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania and Director of Clinical In Vivo Gene Therapy at the Children’s Hospital of Philadelphia. Her laboratory studies the molecular basis of coagulation with a focus on mechanisms that regulate factor VIII/VIIIa cofactor function and developing gene-based therapies for hemophilia A. Dr. George previously led early-phase, adeno-associated virus (AAV) mediated gene transfer trials for hemophilia A and B. Four years ago, she founded the Clinical In Vivo Gene Therapy group at the Children’s Hospital of Philadelphia that provides regulatory support for investigator-initiated studies for IND submission, supports >20 ongoing interventional clinical AAV trials across the institution and oversees the safe and efficient implementation of licensed AAV vectors. Dr. George is a member of the Board of Directors of the American Society of Gene and Cell Therapy and participates in multiple national and international professional societies for hemostasis and gene therapy research.