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c-LEcta is a world-leading biotechnology company with a focus on enzyme engineering and application in regulated markets like the pharma and food industries. c-LEcta’s proprietary GMP endonuclease DENARASE® and the associated ELISA Kit are widely applied in the manufacturing of viral vectors for gene/cell therapies and vaccines, both on clinical and commercial scale. In March c-LEcta launches DENARASE® High Salt - an engineered version of the wild-type Serratia marcescens endonuclease. Compared to the wild-type enzyme, a combination of amino acid substitutions were introduced to provide its increased salt tolerance. Thanks to the great similarity with the wild-type

enzyme, customers can use existing ELISA Kits for the detection of Serratia marcescens endonucleases to monitor residual DENARASE® High Salt. c-LEcta is part of the Kerry Group.

Lean why DENARASE High Salt outcompetes other salt active nucleases at process-relevant, elevated salt concentrations: About DENARASE® High Salt | DENARASE® High Salt | c-LEcta GmbH

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