Professor Melcher is a clinician scientist, and currently Professor of Translational Immunotherapy at The Institute of Cancer Research, London, and Honorary Consultant Oncologist at The Royal Marsden NHS Foundation Trust. He graduated in medicine from the University of Oxford and trained in Clinical Oncology (Radiotherapy and Chemotherapy) in Cardiff, London and Leeds. Following completion of his PhD at the Imperial Cancer Research Fund (now Cancer Research UK) in London, he was a post-doctoral research fellow at the Mayo Clinic, Minnesota, before returning to the UK, where in 2007 he became Professor of Clinical Oncology and Biotherapy at Leeds, before moving to London in 2016. He leads the Institute of Cancer Research/Royal Marsden Hosiptal’s Centre for Immunotherapy of Cancer, and is a group leader in Translational Immunotherapy and Breast Cancer Immunology.