Christian Buchholz heads the Section of Molecular Biotechnology and Gene Therapy at the Paul-Ehrlich-Institut and is Associate Professor for Biochemistry at the Goethe-University in Frankfurt. Being for more than 20 years active in the field, his research focusses on the engineering of gene transfer vectors to understand their cell entry and improve their applicability in molecular medicine. Making use of T-cell targeted vectors his team provided proof-of-principle for in vivo generated human CAR T cells